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DLL3-targeted ADCs currently under investigation for other indications may also have potential in prostate cancer, including ZL-1310, which has shown a favorable safety profile with significant antitumor activity and high response rate in patients with extensive stage SCLC (NCT06179069) 159

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After equilibration was reached, N -ethylmaleimide (NEM, final concentration 40 mM) or iodoacetamide (final concentration 50 mM) were added and a second measurement loop was started

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