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, diabetes, dysbiosis), chemical reactivity enables spontaneous modification, potentiated by glyoxalase system dysregulation: methylglyoxal is converted by glyoxalase 1 (GLO1) to lactoylglutathione (LGSH), which undergoes non-enzymatic acyl transfer to lysine residues (55)
GLP-1 receptors are expressed on immune cells, potentially reducing pro-inflammatory cytokines
Weight management : Older people have a reduced ability to produce glutathione naturally, which can lead to a reduced ability to burn fat, as well as weight gain
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