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The principal site of absorption is the upper jejunum
The FDA recently approved one of these, elamipretide, for the treatment of a rare genetic mitochondrial disorder
As a result, oxidative stress and tissue damage can occur
*Correspondence: Hang Lin, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Tissue Engineering and Regenerative Medicine, a section of the journal Frontiers in Bioengineering and Biotechnology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
HepG2 cells were exposed to synthesized QIs, which bypasses the need for intracellular bioactivation of AQ or DEAQ
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