Rather than both compounds working on the same targets and potentially causing diminishing returns, they address entirely different aspects of metabolism and body composition
In women, OS is implicated in various reproductive disorders, including polycystic ovary syndrome, endometriosis, and premature ovarian failure, leading to diminished oocyte quality, disrupted folliculogenesis, and poorer reproductive outcomes
Additionally, keeping blood sugar stable reduces the risk of complications such as heart disease, which is more common for people with psoriasis and diabetes
4.3.1 Available evidence for natural pregnancy rates and TTP Published meta-analytic summaries and follow-up data from individual trials suggest that GLP-1RA-based metabolic optimization may be associated with higher natural conception rates and shorter time to pregnancy in selected overweight or obese women with PCOS (111, 112, 124)
Metabolic outcomes of elderly patient populations initiating exenatide BID versus insulin glargine in an ambulatory care setting