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If the solution is hazy, contains visible material, or has decolourised, treat it as degraded and discard
For localized injuries, inject subcutaneously near (not into) the affected area when anatomically appropriate
IL-12 can also promote Th1 response, which polarizes macrophage to M1 macrophages (Lu, 2017
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357 IR in adipose tissue leads to high FFAs levels, 358 visceral fat accumulation that is associated with elevated levels of plasminogen activator inhibitor 1 (PAI-1) and BP, 359 and ectopic lipid and toxic lipid metabolite accumulation (lipotoxicity) in blood vessels that alters cellular signaling and cardiac structure, thereby contributing to the increased prevalence of cardiovascular diseases
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