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10.1172/jci194745 J
R.RajendranS.OReillyS.OSullivanG
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A systematic review of drug-drug interactions with GLP-1RAs found that most co-administered oral drugs did not experience clinically significant changes in total exposure (AUC), although reduced peak concentrations (Cmax) and delayed time to peak (Tmax) were commonly observed, particularly for drugs with high solubility and permeability (108)
Indigestion and Heartburn: As food remains in the stomach, stomach acid may back up into the esophagus
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