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Novo Nordisks oral semaglutide is a GLP-1 analogue taken once daily as a tablet, which would be more convenient for patients than treatments administered by injections
Notably, this combination exerts additive or synergistic actions by targeting distinct neuroendocrine pathways: cagrilintide modulates homeostatic and hedonic food regulation centers in the hindbrain and hypothalamus, while semaglutide engages central and peripheral GLP-1 pathways to reduce calorie intake and improve glycemic regulation
Cremonini E, Daveri E, Mastaloudis A, Oteiza PI
Stockwell, B
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