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Weekly VK-2735 subcutaneous injection at a dose of 2.5 mg, 5 mg, 10 mg, and 15 mg resulted in a 9.1%, 10.9%, 12.9%, and 14.7% weight loss, respectively, compared to 1.7% in the placebo group [34]

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ChemistryOpen 6 , 501505 (2017)

G., Huang, Y., Xu, Y

Specifically, these agents have been linked to a range of adverse effects including gastrointestinal dysfunction, kidney disease, and suicidal ideation