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TB-500 is a synthetic version of a short peptide fragment from Thymosin Beta-4 , a naturally occurring protein in almost all human and animal cells

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Animal studies show robust activation of STING in heart, brain, and kidney after IR injury, and genetic or pharmacologic inhibition of STING reduces tissue damage and inflammation ( 2.1.2.4 Inflammasome-independent IL-33 and HMGB1 release Mitochondrial damage can also prompt stressed cells ( e.g

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The presence of this effector gene results in an incompatible plant-bacterium interaction (resistance)