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Because the drugs work in different ways, Ozempic won't replace metformin entirely
College Park, MD, US
Key Phase 3 trials (TRIUMPH-1, -2, -3) are expected to read out by Q4 2026, with NDA submission projected for Q4 2026 to Q1 2027 and a PDUFA target action date of September to October 2027
MASLD Substudy Sanyal et al., Nature Medicine (2024) Sanyal and colleagues conducted a prespecified phase 2a substudy of the original phase 2 obesity trial, evaluating retatrutide in participants with metabolic dysfunction-associated steatotic liver disease (MASLD)
Nutritional Support and Hydration During Tirzepatide Therapy GLP-1 medications like tirzepatide can reduce appetite so significantly that some patients unintentionally under-eat or become dehydratedboth of which increase diverticulitis risk
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