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Mechanistically, Epitalons effect appears to involve a direct interaction with promoter regions of the telomerase gene, where it binds specific DNA sequences (such as ATTTC motifs), potentially modulating transcriptional activity
3-PH can obtain an amino group from glutamate and form 3-phosphoserine (3-PS) through phosphoserine transaminase (PSAT) followed by dephosphorylation through serine phosphatase (PSPH) to finally produce serine (Figure 1)
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