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This targeted, or regioselective, activation of IL-2 may help explain the broader improvements in neuroimmune integration and stress resilience observed in older biological systems

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(2) it relies on murine immune responses, which lack the complexity of the human immune microenvironment

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Evidence also shows that VNS can directly affect ventricular function, particularly in cases of ventricular fibrillation (VF), which is responsible for a significant portion of sudden cardiac deaths (Al-Khatib and Stevenson 2018)