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34 : (Suppl 1) 281281 Pettegrew JW, Moossy J, Withers G, McKeag D, Panchalingam K
It's prescribed alongside changes to diet and activity, as part of a medically supervised plan not on its own, and not as a shortcut
For many patients, the unfamiliar medical language can sound more alarming than the reality itself
It works by: Enhancing insulin secretion in a glucose-dependent manner, which helps lower blood sugar without causing hypoglycemia when used alone Suppressing glucagon release from the pancreas, reducing hepatic glucose production Slowing gastric emptying , which prolongs satiety and reduces appetite Acting on central appetite centers in the hypothalamus to decrease food intake Semaglutide is administered subcutaneously (Ozempic, Wegovy) or orally (Rybelsus) and is primarily eliminated via proteolytic degradation, not through hepatic cytochrome P450 enzymes
doi: 10.1016/j.biopha.2023.114312, 152 ZhengX.ZhangC
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