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Its main role is that it aids the production of energy by transferring fats into cells, known as mitochondria

The global prevalence of CKD is approximately 10% and is increasing, driven by rising rates of type 2 diabetes (T2D) and obesity [1, 4]

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Genetic polymorphisms in Keap1 or Nrf2 further influence individual susceptibility to HTN and response to therapy, highlighting the need for personalized approaches ( 6 Oxidative stress and diabetes mellitus OS in DM operates as both a causal driver and consequential amplifier of disease progression, accelerating metabolic dysfunction and tissue damage in a similar way as in HTN (Kaneto et al., 2022)

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