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TRIUMPH-CVOT, the cardiovascular outcomes trial in roughly 10,000 patients with established cardiovascular disease, is not expected to report until 2028 or 2029, but interim safety reviews matter
Mitochondria are the "powerhouses" of the cell, responsible for producing 9095% of the body's energy in the form of ATP through the electron transport chain
Sodium-glucose co-transporter 2 (SGLT2) inhibitor canagliflozin suppresses TECs apoptosis via maintaining metabolic homeostasis (119), while boeravinone C, an PPAR activator/agonist, can alleviate lipid accumulation and inflammation, thereby suppressing tubular apoptosis (120)
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