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Severe vomiting or dehydration can worsen kidney function, particularly in people who already have kidney disease
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Glucagon acts on adipose tissue to decrease lipogenesis and induce lipolysis
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Since ROS-dependent DNA damage is markedly increased in myeloid cells after Bcr-Abl transformation 18 , we hypothesize that blocking dTTP and dCTP supply might exacerbate replication stress and DNA damage in Bcr-Abl-transformed cells, thereby jeopardizing cell survival
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