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The cost is a real chronic-exposure burden on the myocardium, but it is small in energetic terms the entire resting myocardium consumes only about 170210 kcal/day, so a 1 bpm rise on a base of 70 represents roughly 1.4% of that, on the order of 23 kcal/day
AHK-Cu has far fewer published studies, and much of the evidence supporting its efficacy comes from industry-sponsored reports and patent filings rather than peer-reviewed academic research
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