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An open discussion with your provider about your full health history will help ensure that a compounded GLP-1 medication, if prescribed, is appropriate for your individual situation

In April 2026, NICE recommended semaglutide, alongside a reduced-calorie diet and increased physical activity, to lower the risk of heart attack, stroke or dying of heart disease in people with a BMI (body mass index) of 27 or above who have one of the following: heart attack stroke (caused by a blood clot or bleeding) symptomatic peripheral arterial disease (PAD), such as intermittent claudication with a BPI (brachial pressure index) score of less than 0.85, previous interventions to improve blood flow, or an amputation due to PAD

This is further corroborated by extensive research conducted by Dr

Avoid high-fat, greasy, fried, and very sweet foods during the adjustment period

2.2.1 Lipid peroxidation and Fenton reactions Lipid peroxidation is the core molecular event in ferroptosis (17)