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Extended dosing intervals have limited evidence on long-term safety
Heart Rate Increase: Both adults and pediatric patients experienced mean increases in resting heart rate of 1 to 4 beats per minute (bpm) in semaglutide patients compared to placebo in clinical trials
Most patients notice initial hydration and surface smoothness within 12 weeks
While these medications offer glycemic control and cardiovascular benefits, the risks have increased because of their potential impact on cancer risk, particularly colorectal cancer (CRC)
HRT addresses estrogen and progesterone
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