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More than 100 million people use acetaminophen each year in the U.S
It comprises two GLP-1 analog chains linked to an Fc fragment of IgG4 (not the full antibody, just the Fc), making a large molecule (~63 kDa)
Human liver nicotinamide N-methyltransferase: cDNA cloning, expression, and biochemical characterization
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doi: 10.1111/dom.13804 36 JendleJBirkenfeldALPolonskyWHSilverRUusinarkausKHansenTet al
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