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fda approved glp-1 drugs for weight loss diabetes and weight-loss drug side effects: "Ozempic face" and more Article PBD

Harrison DJ, Kharbanda R, Cunningham DS, McLellan LI, Hayes JD

The selective vulnerability in females led the authors to hypothesize a role for estrogen-linked mechanisms, although this was not tested

COMT is involved in the inactivation of catecholamine neurotransmitters such as epinephrine, norepinephrine, and dopamine, but also catecholestrogens and catechol drugs such as the antiParkinsons disease agent LDOPA and the antihypertensive methyldopa (Weinshilboum et al., 1999)