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The large observed effect size represents an encouraging preliminary finding, as we test our approach for generalizability and robustness to inter-individual variability On toxicity evaluation Any new formulation or drug delivery device that might attempt to replicate the improved targeted deposition at intranasal sites, based on the current findings, will essentially constitute a surface contacting mechanism with limited duration contact

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"The Multifaceted Therapeutic Role of N-Acetylcysteine (NAC) in Disorders Characterized by Oxidative Stress." Curr Neuropharmacol

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Prevention of Further Pigmentation Expert monitoring helps prevent side effects and stops pigmentation from worsening