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10.1016/j.regpep.2012.12.007 7 BecejacT.CesarecV.DrmicD.HirslD.MadzaracG.DjakovicZ.et al (2018)

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Yes, when combined with sunscreen, topical creams, and sometimes laser therapy.However, results are gradual and often require a combination of treatments, such as topical agents, laser therapies, and consistent sun protection, to be truly effective and they do not work as a stand-alone treatment.Claims of instant whitening are not evidence-based

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