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Los niveles circulantes de estos pptidos disminuyen rpidamente tras su liberacin debido al efecto de una enzima proteoltica denominada DPP-4, lo que les confiere una vida media inferior a 2 minutos, siendo el GLP-1 el que ms rpidamente se degrada 2
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In contrast to PIO, rosiglitazone was not shown to promote histologic improvements of NASH during a 12-month well-organized study [65]
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
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