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Research proves GHRH promotes sleep-related GH production
Studies show that depression scores correlate to higher quinolinic acid in the blood, and postmortem studies show more cells in the brain producing quinolinic acid in suicide victims.[ref] Hepatitis C patients treated with interferon-alpha have depression and higher kynurenine metabolites.[ref] Another reason tryptophan metabolism could tilt more towards kynurenine is when the body is lacking in niacin
Systemic effects include fluid retention, arthralgias, and peripheral edema consistent with GH excess
Retatrutide produces higher rates of nausea (43% vs 20-47%), diarrhea (33% vs lower), and vomiting (21% vs lower) at their respective maintenance doses
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