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It has been reported that these three compounds can enhance the contents of GSH and the activities of GSH-dependent antioxidant enzymes (GPX and GST) and reduce lipid peroxidation and cardiac damage mediated by DOX or isoproterenol (ISO) in the myocardium of rats, respectively [121, 129, 130]
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mPGES-1 is coupled with COX-2 and catalyzes the terminal step in the biosynthesis of PGE 2
Die Produktion kann zum Beispiel behindert werden, wenn einer der Vorluferstoffe, eines der bentigten Enzyme oder auch Kofaktoren wie Selen oder Vitamin C nicht in ausreichender Menge zur Verfgung stehen
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