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A phase 2 study randomized participants to bremelanotide 1.25 mg daily and tirzepatide 2.5 mg weekly, bremelanotide alone, tirzepatide alone, and placebo, all for 4 weeks, after a 4-week run in period with tirzepatide 2.5 mg weekly (128)

Outcomes associated with use of a kinin B2 receptor antagonist among patients with COVID-19

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Among participants, AHI decreased by an average of 25.3 events per hour in trial 1 (a 50.7% reduction) and 29.3 events per hour in trial 2 (a 58.7% reduction)