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[5] Drugs
Safety Profile (Phase 2) The most common adverse events were gastrointestinal and consistent with the incretin drug class: - Nausea - Diarrhea - Vomiting - Constipation - Decreased appetite These GI events were dose-related, mostly mild to moderate, and partially mitigated by starting at a lower initial dose (2 mg vs
In preclinical models, it increases insulin release and decreases glucagon, which is the activation of GLP-1 receptors
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Pain varies by individual
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