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These genes are potentially implicated in HFHFD-induced pathophysiological processes, such as inflammation, oxidative stress, and metabolic disturbances
These complexes are anchored by the 5 helix of G s , which fits to the cytoplasmic cavity formed by TMs 2, 3, 5, 6, 7 and intracellular loop 1 (ICL1)
[9] It shows promise for HFpEF and cardiovascular protection , reducing inflammation, and improving heart and vascular health
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