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Um estudo de Sikiric et al
Three groups were identified: participants with current MDD (that is, participants meeting DSM-IV criteria for MDD within the past 6 months), with remitted (i.e., lifetime but not current) MDD, and healthy controls (without any lifetime depressive/anxiety disorder)
Discovery of AG-270, a first-in-class oral MAT2A inhibitor for the treatment of tumors with homozygous MTAP deletion
The chart below shows timing considerations for common combinations
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