If youre using Zepbound for obstructive sleep apnea , gastrointestinal symptoms like nausea and fatigue may appear earlier due to the metabolic impact of rapid weight reduction
You can also dispose of used Ozempic pens in the sharps container
When to Call Your Provider Reach out to your prescribing provider, rather than managing it alone, if you experience: Vomiting that prevents you from keeping fluids down for more than 24 hours Severe or worsening abdominal pain, particularly if it radiates to your back Signs of dehydration: dark urine, dizziness upon standing, or a noticeably reduced need to urinate Symptoms of low blood sugar, especially if youre also on insulin or another diabetes medication Any symptom that feels disproportionate to what you were told to expect Theres no such thing as a question too small to ask your care team when youre adjusting to a new medication
SURPASS-4 confirmed no significant increase in risk of cardiovascular disease with tirzepatide in a high-risk population, and a pre-specified meta-analysis demonstrated a hazard ratio of 0.8 for major adverse cardiovascular events (cardiovascular death, non-fatal stroke or myocardial infarction, or hospitalisation for unstable angina) over 55 weeks
[50] Zhu D, et al