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Antihyperalgesic effects of (R,E)-N-(2-hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a novel transient receptor potential vanilloid type 1 modulator that does not cause hyperthermia in rats
NatureMedicine;2;847-9
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Leeuwenburgh C, et al
doi: 10.3389/fnut.2026.1822840 Received 04 March 2026 Revised 27 April 2026 Accepted 29 April 2026 Published 20 May 2026 Corrected 28 May 2026 Volume 13 - 2026 Edited by Camelia Munteanu, University of Agricultural Sciences and Veterinary Medicine of Cluj-Napoca, Romania Reviewed by Yasutaka Shigemura, Tokyo Kasei University, Japan Cornelia Witthft, Linnaeus University, Sweden Updates Copyright 2026 Haarhuis, Ahn-Jarvis, Savva, Day-Walsh, Ferns, Hughes, Triller, Al-Jaibaji, Philo, Acaroz, Perez-Moral and Kroon
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