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This new study used the TriNetX US Collaborative Network platform, which contains data from nearly 120 million patients, and the researchers applied rigorous propensity matched cohorts of patients prescribed GLP-1 receptor agonists, alternate glucose-lowering meds or lipid-lowering drugs

Take peptides that traditionally required injection and make them accessible through oral delivery

doi: 10.1152/japplphysiol.00599.2016

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That is an important framing for anyone tempted to treat it as a shortcut: even in the animal work that generates the interest, the compound is one input alongside energy balance, not a replacement for it