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doi: 10.1038/nature21370 120 JinH.XuM.ChenH.ZhangS.HanX.TangZ.et al
Rev Environ Contam Toxicol 227:153
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Healthy aging is defined as the accumulation of time dependent cellular damage which factors include oxidative stress, epigenetic changes, genomic instability, telomere attrition, and dysregulation of cell signaling and inflammatory responses, upon further hit, this natural disruption may become detrimental [53]
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