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Metformin (for diabetes), proton pump inhibitors (such as omeprazole or esomeprazole), and H2 blockers (such as famotidine) can all reduce B12 absorption over time

NNMT is a cytosolic enzyme that plays a significant rolein metabolism and energy and is predominantly active in fat tissue

Methylation is a fundamental biochemical process involved in detoxification, hormone metabolism, neurotransmitter production, DNA repair, and gene expression

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If passed, it would fundamentally change the tirzepatide billing landscape for Medicare patients