Drugs ORAL HYPOGLYCEMICS: : glyburide, glipizide, glimepiride Sulfonylureas : repaglinide, nateglinide Glinides : metformin Biguanide : acarbose, miglitol -Glucosidase Inhibitors Thiazolidinediones or : pioglitazone, rosiglitazone Glitazones 1) : bromocriptine Dopamine agonist : canagliflozin, dapagliflozin, empagliflozin SGLT-2 Inhibitors : sitagliptin, saxagliptin, linagliptin, alogliptin DPP-IV Inhibitors INJECTIBLE HYPOGLYCEMICS : : exenatide, lixisenatide, liraglutide, albiglutide, dulaglutide, semaglutide GLP-1 Agonists : pramlintide Amylin Analog BILE ACID SEQUESTRANTS: colesevelam INSULINS: PRANDIAL: : lispro, aspart, glulisine, inhaled Rapid acting : regular crystalline zinc Short-acting BASAL: : NPH (or Isophane) Intermediate acting : glargine, detemir Long acting : degludec Ultra-long acting INSULIN + GLP1 COMBINATIONS: glargine + lixisenatide (Soliqua ) degludec + liraglutide (Xultophy ) GOALS OF THERAPY Figure X
These therapeutic approaches are currently regarded as experimental and off-label, and patients should be fully informed of the limited empirical support for their efficacy and safety in these contexts
It typically peaks during the first few days after your injection and improves before your next dose
At its core, the appeal lies in rhythm and pacing: the screen breathes, the stakes rise and fall, and the player decides when to commit and when to wait
Success feeds success
