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The specific vulnerability of the gastrointestinal system to TD, in the absence of more common signs of wet and dry beriberi, may arise from direct exposure of this system to the gut microbiome and oral drugs, along with the continuous need to redistribute thiamine to other tissues

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Compounded Low-Dose Naltrexone Off-Label Immune/Neuroimmune Modulator Low-Dose Naltrexone (LDN) is sometimes incorporated as a select-case adjunct when the clinical picture is complex or symptoms persist despite standard mast celldirected therapy