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Heavy metals, such as lead, mercury, and cadmium, can deplete glutathione levels, impairing the body's ability to detoxify harmful substances and reducing the availability of SAMe for methylation

Moreover, intersections between upregulated DEGs in the control group and downregulated DEGs in the treatment groups, as well as between downregulated DEGs in the control group and upregulated DEGs in the treatment groups, also demonstrated that the combination group had a greater overlap with the control group than either single-drug group did (Additional file 2: Figure S5)

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Storage & handling: Store the lyophilized vial refrigerated at 28C, protected from light and heat

Individuals with a bleeding disorder or who take blood thinners