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Mixing mcg into a calculation that expects mg shifts the answer by 1000x a documented cause of users either taking a microscopic dose or a fatal-equivalent dose depending on which direction the unit error went

Nitrous oxide-induced B deficiency myelopathy: Perspectives on the clinical biochemistry of vitamin B

According to the National Institutes of Health, only about 1 to 2 percent of an oral dose actually makes it into your bloodstream

Effective for Many People: They work well for individuals with mild deficiencies or those who need to supplement their diet, such as vegans and vegetarians