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This distinction affects how the compound is absorbed, metabolized, and utilized in the body
[1] Those who cannot digest or absorb B12 as a result of inherited genetics or damage to the stomach and small intestine require more than can be absorbed from sublingual supplementation
In all these cases, the goal is to correct deficiency and prevent complications
Nausea incidence is similar, affecting 25-35% of users on both drugs
If this approach holds up in bigger studies, it could be a meaningful option for people whose chronic pain has not responded to standard treatments
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