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Increased risk of diarrhea-predominant irritable bowel syndrome (IBS-D) Increased insulin resistance and glucose intolerance, contributing to elevated blood glucose Poor wound healing, altered taste and smell, and changes in cognitive function, particularly in older adults How common is zinc deficiency
If youre prone to GI side effects, consume a small protein-rich snack (15-20g protein, minimal fat) 30 minutes before injection to buffer the gastric effect without interfering with the meal-timing strategy
Oral supplements may be enough
PMID 11817985
Clinical Trial Outcomes with Monotherapy The REDEFINE 1 trial demonstrated that cagrilintide monotherapy at the 4.5 mg maintenance dose produced mean body weight reductions of approximately 10.8% from baseline after 32 weeks of treatment [4]
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