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As far as CRF1R, CRF2R, AM1R, AM2R and CLR are concerned, their ECL1 are relatively short (consisting of 811 residues) and can only form one-turn -helix to connect the adjacent transmembrane helices TM2 and TM3, contributing limited contacts with the peptides
*Genealogy and Human Health*, 2013
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The abdomen (at least 2 inches from the navel), outer thigh, and back of the upper arm are all suitable locations
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