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CagriSema produced mean weight loss of 13.7% at 68 weeks compared to 3.4% with placebo, with an on-treatment estimate of 15.7%
The higher doses and costs are justified by accelerated timelines in appropriate contexts
Because clearance is slow, an intolerable dose cannot be reversed quickly discontinuation does not produce prompt washout
Oral supplements and topical products may be available without a prescription, though physician guidance is still recommended
But we know it can take studies time to catch up and people are eager to seek out alternatives to optimize their health now, not just fix problems later
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