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The methylation cycle is entirely dependent on a steady supply of specific B-vitamins acting as coenzymes, particularly Vitamin B9 (folate), Vitamin B12 (cobalamin), Vitamin B6, and Vitamin B2 (riboflavin)
Moreover, the risk of hospitalizations, cardiovascular disease, and mortality was found to be high in the concurrent presence of these two conditions [24,25,26,27,28]
The epithelial layer remained intact, with no significant changes in goblet cell distribution or mucus production
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