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In summary, future clinical trials should prioritize enrolling individuals at risk, followed by those in the early stages of the disease, as this offers a higher likelihood of demonstrating neuroprotective and disease-modifying effects

Soria-Contreras, Lydia Shook, Christopher Mow, Marie-France Hivert, and Tanayott Thaweethai.

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Therefore, GIP Ile 12 could function as a spatial obstruction, for example restricting GIPR Arg 289 so that it interacts with GIP Asp 15 rather than Asp 9 (as a modeling in RCSB PDB: 7DTY, )

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