* Its not for people who have a personal history of pancreatitis or allergy to GLP-1 medications, or a personal or family history of medullary thyroid cancer or multiple endocrine neoplasia type 2, or people with type 1 diabetes
Furthermore, its tolerability profile, which includes weight gain, edema/fluid retention, fractures, and (rarely) bladder cancer in long-term use, could hinder its potential repositioning for depression [173]
Section 503B outsourcing facilities are a higher-tier designation: they undergo FDA inspections, follow current Good Manufacturing Practice (cGMP) standards similar to pharmaceutical manufacturers, and are permitted to compound larger quantities for office use in addition to individual prescriptions
Children and adolescents often struggle to get enough sleep
Known for its use in managing type 2 diabetes, Metformin can also help with weight loss