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Nature 444 : 881887 Nogueiras R et al
Some substances may face more scrutiny than others based on available safety data or the adequacy of evidence supporting the nominated uses
While short-term or single-cycle AAS use is often followed by partial or complete restoration of hypothalamicpituitarygonadal (HPG) axis function, prolonged or repeated exposure to supraphysiological doses is associated with an increased risk of incomplete or delayed recovery
Studies in melanocyte cell lines and receptor-transfected systems have characterised the cAMP signalling response, tyrosinase induction, and melanin output associated with MT-1 receptor engagement
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