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Indeed, the history of anti-obesity medications has been marked by several failures due to serious adverse events, such as suicidality, observed only after their usage had become extensive 221,234 a well-known example being the one that led to the withdrawal of the endocannabinoid inverse agonist, rimonabant 235

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doi: 10.1152/physiol.00031.2023 33

05 Storage mistake If a reconstituted vial was left at room temperature for more than a few hours, treat it as compromised

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