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What they did: A very harsh model, they ligated the inferior vena cava (vena cava inferior) in rats, which is the main channel for blood returning to the heart
Although more data is needed from RCTs and there are indeed cost challenges, the GLP-1RAs have, in my opinion, significant potential clinical implications in treatment of other disease states as well
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I was lethargic, didn't want to do anything, couldn't make any gains in the gym, and couldnt lose weight, he says
PMID 17371789
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