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HCV-induced ROS play a significant role in HCV pathogenesis, as Kupffer cell activation contributes to pro-fibrotic cytokine and ROS production, leading to hepatic damage 91,92
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Moreover, baseline LBP and sCD14 levels were similar in patients with normal (2/3 of patients) and increased intestinal permeability (urinary 51 Cr-EDTA excretion), highlighting again that bacterial translocation is not a paracellular phenomenon and that one should be careful of connecting clinical outcomes to paracellular permeability tests (149)
The main difference between PepT1 and PHTs is that the PHTs can transport l-histidine, in addition to di/tripeptides
Degenhardt, K
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